Definition of plague. a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal; an annoyance; "those children are a damn plague"; any epidemic disease with a high death rate; any large scale calamity (especially when thought to be sent by God)The Plague. The first outbreak of plague swept across England in 1348-49. It seems to have travelled across the south in bubonic form during the summer months of 1348, before mutating into the ...Plague is a febrile illness that typically manifests into one or more clinical syndromes, often reflecting the route of exposure to the bacterium. These clinical syndromes include bubonic, septicemic, and pneumonic plague. Several classes of antibiotics are effective against plague. Plague can be rapidly fatal if appropriate antimicrobial ... The plague bacteria can be transmitted to humans in the following ways: Flea bites. Plague bacteria are most often transmitted by the bite of an infected flea. During plague epizootics, many rodents die, causing hungry fleas to seek other sources of blood. People and animals that visit places where rodents have recently died from plague are at ...Apr 7, 2020 · Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ... Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Recent Reviews: Overwhelmingly Positive (361) May 7, 2020 · The plague as an actual event figures prominently in only one of Shakespeare’s plays. Friar Laurence in “Romeo and Juliet” has asked a fellow friar to deliver a crucial message to the exiled ... Nov 16, 2022 · Over 80% of United States plague cases have been the bubonic form. In recent decades, an average of seven human plague cases have been reported each year (range: 1–17 cases per year). Plague has occurred in people of all ages (infants up to age 96), though 50% of cases occur in people ages 12–45. It occurs in both men and women, though ... Aug 6, 2021 · Plague is a disease that affects humans and other mammals. It is caused by the bacterium, Yersinia pestis. Humans usually get plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with plague. Plague is infamous for killing millions of people in Europe during the Middle Ages. The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days.Feb 28, 2022 · The plague is a serious bacterial infection that can be deadly. Sometimes referred to as the “black plague,” the disease is caused by a bacterial strain called Yersinia pestis.This bacterium ... The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived.plague ý nghĩa, định nghĩa, plague là gì: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Tìm hiểu thêm. Nov 26, 2019 · Plague is a plausible diagnosis for people who are sick and live in, or have recently traveled to, the western United States or any other plague-endemic area. The most common sign of bubonic plague is the rapid development of a swollen and painful lymph gland called a bubo. A known flea bite or the presence of a bubo may help a doctor to ... Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.Responding to a Plague Bioterrorism Event. Kettles, buckets, lanterns, and other equipment were used in catching rats during the Public Health Service campaign against the New Orleans plague epidemic of 1914-1920. (Library of Medicine) Page last reviewed: February 7, 2022. Content source: Centers for Disease Control and Prevention, National ...Oct 1, 2021 · Plague is endemic in Madagascar and outbreaks occur regularly, although every outbreak is cause for concern. Furthermore, pneumonic plague is a notifiable disease under the International Health Regulations 2005. By the following day, 30 August, 25 suspected cases of pneumonic plague had been notified to the health authorities from Arivonimamo ... Find 86 ways to say PLAGUE, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus.plague: [noun] a disastrous evil or affliction : calamity. a destructively numerous influx or multiplication of a noxious animal : infestation. Aug 23, 2023 · Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Brilliantly executed with innovative gameplay and built ... Plague is an infectious disease caused by the bacteria Yersinia pestis, a zoonotic bacteria, usually found in small mammals and their fleas. It is transmitted between animals from their fleas. Humans can be contaminated by the bite of infected fleas, through direct contact with infected materials or by inhalation.Mar 28, 2023 · Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ... Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms.Plague is a febrile illness that typically manifests into one or more clinical syndromes, often reflecting the route of exposure to the bacterium. These clinical syndromes include bubonic, septicemic, and pneumonic plague. Several classes of antibiotics are effective against plague. Plague can be rapidly fatal if appropriate antimicrobial ...Jun 15, 2023 · The disease is most common in parts of Africa, Asia and South America, but it also occurs in some areas of the western United States. Symptoms can include an abrupt onset of chills, fever, and enlarged, painful lymph nodes (buboes). Most cases of plague resolve with effective treatment, though treatment must be started immediately to avoid life ... Over 80% of United States plague cases have been the bubonic form. In recent decades, an average of seven human plague cases have been reported each year (range: 1–17 cases per year). Plague has occurred in people of all ages (infants up to age 96), though 50% of cases occur in people ages 12–45. It occurs in both men and women, though ...a serious disease that kills many people, often used to refer to bubonic plague, a very infectious disease caused by bacteria spread mainly by fleas (= small insects that bite) on rats or other animals, that causes swelling, fever, and usually death in humans:Evidence suggests Washtenaw County’s criminal legal system is rife with disparities based on race, and those are among the 65 recommendations of a sprawling new report released on Aug. 31 that ...Oct 29, 2020 · Plague is a serious infectious disease that affects mammals, including humans. It can spread through animal or human contact. The bacteria that cause plague live in many parts of the world ... Oct 29, 2020 · Plague is a serious infectious disease that affects mammals, including humans. It can spread through animal or human contact. The bacteria that cause plague live in many parts of the world ... Methods. CDC developed these guidelines after reviewing existing data on treatment and prophylaxis of plague, collecting and summarizing additional evidence, and gathering input from approximately 90 experts in numerous fields, including infectious diseases, emergency medicine, pharmacology, neonatology, obstetrics and gynecology, geriatrics, microbiology, epidemiology, and crisis standards of ...The plague bacteria can be transmitted to humans in the following ways: Flea bites. Plague bacteria are most often transmitted by the bite of an infected flea. During plague epizootics, many rodents die, causing hungry fleas to seek other sources of blood. People and animals that visit places where rodents have recently died from plague are at ...Jul 7, 2022 · Plague is an infectious disease caused by the bacteria Yersinia pestis, a zoonotic bacteria, usually found in small mammals and their fleas. It is transmitted between animals through fleas. Humans can be infected through: the bite of infected vector fleas. unprotected contact with infectious bodily fluids or contaminated materials. Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Brilliantly executed with innovative gameplay and built ...Here’s how five of the world’s worst pandemics finally ended. 1. Plague of Justinian—No One Left to Die. Yersinia pestis, formerly pasteurella pestis, was the bacteria responsible for the ...May 7, 2020 · The plague as an actual event figures prominently in only one of Shakespeare’s plays. Friar Laurence in “Romeo and Juliet” has asked a fellow friar to deliver a crucial message to the exiled ... The terms the plague or just plague (without the or a) refer to an infectious disease caused by a bacterium spread from rats to humans by means of flea bites. This plague is what is meant by the Black Death , which was a form of bubonic plague that spread over Europe in the 1300s and killed about a quarter of the population.Sudden high fever and chills. Pains in the areas of the abdomen, arms and legs. Headaches. Large and swollen lumps in the lymph nodes (buboes) that develop and leak pus. Symptoms of septicemic plague may include blackened tissue from gangrene, often involving the fingers or toes, or unusual bleeding.In the 17th century, people believed these outfits could purify poisonous air. They were wrong. During the 17th-century European plague, physicians wore beaked masks, leather gloves, and long ...Plagues of Egypt. Scenes from the book of Exodus: The death of the firstborns (including the Pharaoh 's son), and the Israelites leaving Egypt ( Haggadah shel Pesaḥ, 1325–1374 CE, Barcelona via British Library) The Plagues of Egypt, in the account of the book of Exodus, are ten disasters inflicted on Biblical Egypt by the God of Israel in ... Definition of plague. a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal; an annoyance; "those children are a damn plague"; any epidemic disease with a high death rate; any large scale calamity (especially when thought to be sent by God) “[Blurbs] are a PLAGUE on this industry” said Lucy Carson (emphasis her own), a literary agent at The Friedrich Agency who has worked with literary bigwigs like Pulitzer Prize-winner Elizabeth ...PLAGUE. Plague is a disease of rodents and their fleas that can be transmitted to humans. Throughout history, plague, often referred to as the " Black Death ," has caused catastrophic pandemics resulting in deaths of tens of millions of persons. The disease is caused by a gram-negative bacterium, Yersinia pestis.Plague is caused by Yersinia pestis bacteria. It can be a life-threatening infection if not treated promptly. Plague has caused several major epidemics in Europe and Asia over the last 2,000 years. Plague has most famously been called "the Black Death" because it can cause skin sores that form black scabs. A plague epidemic in the 14th century ...Evidence suggests Washtenaw County’s criminal legal system is rife with disparities based on race, and those are among the 65 recommendations of a sprawling new report released on Aug. 31 that ..."Plague is a must-read book so revolutionary in its implications that its author courageously faced character assassination and unlawful incarceration to keep her findings from being relegated to the dustbin of medical history. Riveting, if not at times paradigm shifting, this book reveals a dark side to modern mediJul 22, 2021 · The 10-year-old child who died of plague earlier this month was a La Plata County resident. Plague is caused by bacteria and usually is transmitted by bites from infected fleas. Prairie dogs ... The plague of Justinian or Justinianic plague (541–549 AD) was a bubonic plague epidemic and the first recorded major outbreak of the first plague pandemic: the first Old World pandemic of plague, the contagious disease caused by the bacterium Yersinia pestis. The disease afflicted the entire Mediterranean Basin, Europe, and the Near East ...The terms the plague or just plague (without the or a) refer to an infectious disease caused by a bacterium spread from rats to humans by means of flea bites. This plague is what is meant by the Black Death , which was a form of bubonic plague that spread over Europe in the 1300s and killed about a quarter of the population.Apr 20, 2023 · Plague symptoms are sudden and serious. If you are coughing or sneezing, you should wear a mask. You will likely go to an emergency room. If plague is suspected, you'll see a specialist in infectious disease. What you can do. If you are helping a person with plague-like symptoms, you can prepare for the appointment by taking the following steps: Aug 23, 2023 · Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Brilliantly executed with innovative gameplay and built ... Jul 23, 2021 · The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived. plague of [sth] n. figurative ( [sth] bad and persistent) ~의 재앙 명. Anna has suffered a plague of misfortunes. 안나는 불운의 재앙을 겪었다. plague [sb/sth] ⇒ vtr. figurative, often passive (afflict) ~에 피해를 주다, ~을 괴롭히다. That country has been plagued by misfortune.The plague hits Marseille, Paris and Normandy, and then the strain splits, with one strain moving onto the now-Belgian city of Tournai to the east and the other passing through Calais. and Avignon ...Find 86 ways to say PLAGUE, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus.Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms.Mar 28, 2023 · Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ... The plague is a serious bacterial infection that can be deadly. Sometimes referred to as the “black plague,” the disease is caused by a bacterial strain called Yersinia pestis.This bacterium ...Sep 7, 2023 · Blurbs expose this ecosystem for what it really is: a nepotism-filled system that everyone endures for a chance of “making it” in an impossible industry for most. To borrow a phrase from ... Treatment for plague begins as soon as the health care provider suspects the disease. Treatment is typically done in the hospital. Antibiotics that may be used include the following: Gentamicin. Doxycycline (Monodox, Vibramycin, others). Ciprofloxacin (Cipro). Levofloxacin. Moxifloxacin (Avelox). Chloramphenicol.Pneumonic plague transmission Although plague can sometimes spread from person to person, this is rare.1 A person who has pneumonia caused by plague may cough up droplets that contain plague bacteria. These bacteria-containing droplets can cause pneumonic plague if they are breathed in by another person nearby.Sep 24, 2020 · History of Plague Epidemics. The plague has afflicted humanity for thousands of years.1, 2, 3 Molecular studies identified the presence of the Y. pestis plague DNA genome in 2 Bronze Age skeletons dated at roughly 3800 years old. 9 In the biblical book 1 Samuel from approximately 1000 BCE, the Philistines experience an outbreak of tumors associated with rodents, which might have been bubonic ... Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2] Plague was present in at least one location in the Islamic world virtually every year between 1500 and 1850. [56] Plague repeatedly struck the cities of North Africa. Algiers lost 30,000–50,000 to it in 1620–1621, and again in 1654–1657, 1665, 1691, and 1740–1742. [57]Oct 12, 2016 · The plague laid siege to the city of London several times during the 16th and 17th centuries, most famously between 1665 and 1666. The pestilence first arose in the suburb of St. Giles-in-the ... Synonyms for PLAGUE: afflict, persecute, torture, besiege, curse, attack, beset, torment; Antonyms of PLAGUE: help, aid, assist, relieve, release, deliver, abet, comfortWright — a staff writer at The New Yorker, where the article that “The Plague Year” is based on first appeared — has performed a virtuoso feat and given us a book of panoramic breadth. It ...Nov 16, 2022 · Over 80% of United States plague cases have been the bubonic form. In recent decades, an average of seven human plague cases have been reported each year (range: 1–17 cases per year). Plague has occurred in people of all ages (infants up to age 96), though 50% of cases occur in people ages 12–45. It occurs in both men and women, though ... plague ý nghĩa, định nghĩa, plague là gì: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Tìm hiểu thêm. Plague, infectious disease caused by Yersinia pestis, a bacterium transmitted from rodents to humans by the bite of infected fleas. Plague has caused some of the most-devastating epidemics in history. It was the disease behind the Black Death of the 14th century, when as much as one-third of Europe’s population died.Bubonic plague: Humans can come into contact with plague when an infected flea bites a person or when materials that have plague bacteria enter through a break (a cut or sore) in a person's skin. This is the most common form of plague. Pneumonic plague: Humans can come into contact with plague when a person breathes in plague bacteria from the air.Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Recent Reviews: Overwhelmingly Positive (361)List of epidemics and pandemics. 17th-century German "plague panel" depicting the triumph of death. Panels of this kind were placed on the walls of houses to warn against the plague. A plague epidemic raged in Augsburg, Bavaria, between 1632 and 1635. This is a list of the largest known epidemics and pandemics caused by an infectious disease. Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts.Mar 26, 2020 · Collection. by Mark Cartwright. published on 26 March 2020. Plagues have swept through humanity ever since communities have gathered together in concentrated groups. In this collection of resources, we look at just some of the pandemics that raged throughout Antiquity and the Middle Ages, from the plague that ripped through Athens in the 5th ... Jul 22, 2021 · The 10-year-old child who died of plague earlier this month was a La Plata County resident. Plague is caused by bacteria and usually is transmitted by bites from infected fleas. Prairie dogs ... Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2] Jun 15, 2023 · The disease is most common in parts of Africa, Asia and South America, but it also occurs in some areas of the western United States. Symptoms can include an abrupt onset of chills, fever, and enlarged, painful lymph nodes (buboes). Most cases of plague resolve with effective treatment, though treatment must be started immediately to avoid life ... plague n. (infestation of insects or rats) invasion nf. (de moustiques, sauterelles,...) nuée nf. The citizens of Hamlin called on the services of the Pied Piper because of a plague of rats. Les citoyens de la ville de Hamelin ont fait appel au service du joueur de flûte à cause d'une invasion de rats. plague n. Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly. Plague, infectious disease caused by Yersinia pestis, a bacterium transmitted from rodents to humans by the bite of infected fleas. Plague has caused some of the most-devastating epidemics in history. It was the disease behind the Black Death of the 14th century, when as much as one-third of Europe’s population died.Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Recent Reviews: Overwhelmingly Positive (361) Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ...Oct 1, 2021 · Plague is endemic in Madagascar and outbreaks occur regularly, although every outbreak is cause for concern. Furthermore, pneumonic plague is a notifiable disease under the International Health Regulations 2005. By the following day, 30 August, 25 suspected cases of pneumonic plague had been notified to the health authorities from Arivonimamo ... The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days. Pneumonic plague transmission Although plague can sometimes spread from person to person, this is rare.1 A person who has pneumonia caused by plague may cough up droplets that contain plague bacteria. These bacteria-containing droplets can cause pneumonic plague if they are breathed in by another person nearby.
What is plague? Plague is a disease caused by Yersinia pestis that affects rodents (e.g., squirrels, prairie dogs, or mice), other mammals (e.g., rabbits or hares), and humans. These bacteria are found in many areas of the world, including the western United States. There are three forms of plague: bubonic (lymph node infection), pneumonic (lung […] . C37d00bf730d30dff802aeaccc6bc50f.jpgandquot
Nov 26, 2019 · Plague is a plausible diagnosis for people who are sick and live in, or have recently traveled to, the western United States or any other plague-endemic area. The most common sign of bubonic plague is the rapid development of a swollen and painful lymph gland called a bubo. A known flea bite or the presence of a bubo may help a doctor to ... Plague. Plague, caused by the bacterium Yersinia pestis, is a disease that affects humans and other mammals. People typically get infected after being bitten by a rodent flea that is carrying the bacterium or by handling a plague-infected animal. Although the disease killed millions in Europe during the Middle Ages, antibiotics effectively ...Definition of plague. a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal; an annoyance; "those children are a damn plague"; any epidemic disease with a high death rate; any large scale calamity (especially when thought to be sent by God)Sep 7, 2023 · Blurbs expose this ecosystem for what it really is: a nepotism-filled system that everyone endures for a chance of “making it” in an impossible industry for most. To borrow a phrase from ... Plague is a serious illness caused by a germ called Yersinia pestis. The germs mostly live in small rodents and their fleas. The most common way for humans to get plague is a flea bite. Plague is a rare disease. The illness mostly occurs in only a few countries around the world.Evidence suggests Washtenaw County’s criminal legal system is rife with disparities based on race, and those are among the 65 recommendations of a sprawling new report released on Aug. 31 that ...Aug 29, 2023 · The Latin word also is the source of Old Irish plag (genitive plaige) "plague, pestilence," German Plage, Dutch plaage. Meaning "epidemic that causes many deaths" is from 1540s; specifically in reference to bubonic plague from c. 1600. Modern spelling follows French, which had plague from 15c. Weakened sense of "anything annoying" is from c. 1600. Oct 29, 2020 · Plague is a serious infectious disease that affects mammals, including humans. It can spread through animal or human contact. The bacteria that cause plague live in many parts of the world ... The disease is most common in parts of Africa, Asia and South America, but it also occurs in some areas of the western United States. Symptoms can include an abrupt onset of chills, fever, and enlarged, painful lymph nodes (buboes). Most cases of plague resolve with effective treatment, though treatment must be started immediately to avoid life ...Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ...Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts.plague of [sth] n. figurative ( [sth] bad and persistent) serie, ondata nf. Anna has suffered a plague of misfortunes. Anna è stata vittima di una serie di disgrazie. plague [sb/sth] ⇒ vtr. figurative, often passive (afflict) (figurato) flagellare ⇒ vtr. That country has been plagued by misfortune. Black Death. The Black Death (also known as the Pestilence, the Great Mortality or the Plague) [a] was a bubonic plague pandemic occurring in Western Eurasia and North Africa from 1346 to 1353. It is the most fatal pandemic recorded in human history, causing the deaths of 75–200 million people, [1] peaking in Europe from 1347 to 1351.The plague of Justinian or Justinianic plague (541–549 AD) was a bubonic plague epidemic and the first recorded major outbreak of the first plague pandemic: the first Old World pandemic of plague, the contagious disease caused by the bacterium Yersinia pestis. The disease afflicted the entire Mediterranean Basin, Europe, and the Near East ...Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Brilliantly executed ... plague definition: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Learn more. .